The senior national team have jetted off to the host country on Saturday morning after an earlier cancellation of their trip due to bad weather.
Coach Avram Grants and his charges are poised to win the 31st edition of the competition.
His Excellency has tasked the Black Stars to go and win the AFCON title
"Best wishes to the players, technical & management team of the Black Stars. Time to end our 34 year wait for the AFCON trophy. Go for gold!" the President wrote on his official twitter account.
Ghana will open their campaign for 2017 AFCON with Uganda on Tuesday.