The sole African nation left in the mundial begin the game level on four points with Japan in Group H.
Aliou Cisse's men looked set to qualify in their previous game but gave up the lead to the Blue Samarai,after goals from Sadio Mane and Molla Wogue.
Colombia swept aside Poland in their second match,after losing to Japan in their opening game with Yerri Mina, Falcao and Juan Cuadrado ensuring the South Americans clinch all three points.
Midfielder Aguillar Abel has been ruled out for Colombia with a thigh injury,whiles their reliable goalkeeper David Ospina has fully recovered.
Both teams are aware a win will take them through with Senegal assured of progressing to the next stage with only a draw.
Predicted Senegal XI: Ndiaye; Sabaly, Koulibaly, Sane, Wague; Kouyate, Ndiaye, Gueye; Mane, Niang, Sarr
Colombia Predicted XI: Ospina; Arias, D. Sanchez, Mina, Mojica; Uribe, C. Sanchez, Cuadrado, Quintero, James Rodriguez; Falcao
By: Ishaak Hussein Shakino